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Ce in which the N-terminus of the CTD (residues 145?51 in the full-length protein) fit into a helical groove on the symmetric subunit, as confirmed by the observation of several intersubunit NOEs (PDB ID 2KOD). Here, we have used the chemical shift assignments from solid-state NMR experiments reported in reference 29 and backbone N and CR R RDCs measured in solution28 as the only source of experi
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Ce in which the N-terminus of the CTD (residues 145?51 in the full-length protein) fit into a helical groove on the symmetric subunit, as confirmed by the observation of several intersubunit NOEs (PDB ID 2KOD). Here, we have used the chemical shift assignments from solid-state NMR experiments reported in reference 29 and backbone N and CR R RDCs measured in solution28 as the only source of experi
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Cludes several genes that are involved in drug metabolism and disposition. Xenobiotic Phase I and II biotransformation enzyme genes induced by BaP include genes encoding a cytochrome P450 family 3 (CYP3-like-2, CBY21750), carboxylesterase, glutathione S-transferase alpha (GSTa), thiosulfate sulfurtransferase and thioredoxin. Genes encoding Phase III transport proteins, ABC transporters and solute
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Tion virosomes and virosomal adjuvanted formulations are currently applied in commercialTion virosomes and virosomal adjuvanted formulations are currently applied in commercial vaccines (Hepatitis A vaccines: Epaxal and Epaxal junior; Influenza vaccines: Inflexal V and FluAd). Moreover several promising virosome vaccine candidates , (Malaria, HCV breast cancer HIV Candida vaccines) are , , ,
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Arbon benzo[a]pyrene (BaP) the pharmaceutical compound Clofibrate (Clo). Results: Oikopleura genome surveys for key genes of the chemical defensome suggested a reduced repertoire. Not more than 23 cytochrome P450 (CYP) genes could be identified, and neither CYP1 family genes nor their transcriptional activator AhR was detected. These two genes were present in deuterostome ancestors. As in vertebra
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Ards Initiative. Competing interests The authors declare that they have no competing interests. Authors' contributions MA infected the animals, collected samples, ran gels, did preliminary analysis, and assisted with the writing of the manuscript. TMU organized and analyzed data, and participated in the writing of the manuscript. RH assisted with animal work and gels and helped with preliminary an
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S low-cost, nonreplicating, non-integrating, non-pathogenic E2 vaccines could be designed andS low-cost, nonreplicating, non-integrating, non-pathogenic E2 vaccines could be designed and combined with other approaches to advance the field of vaccinology.CONCLUSIONVaccines play a pivotal role in host protection against infectious diseases and have significantly reduced mortality worldwide. Ho